An avian pathogenic Escherichia coli isolate induces caspase 3/7 activation in J774 macrophages
نویسندگان
چکیده
منابع مشابه
Characterization of Escherichia coli DNA lesions generated within J774 macrophages.
Macrophages are armed with multiple oxygen-dependent and -independent bactericidal properties. However, the respiratory burst, generating reactive oxygen species, is believed to be a major cause of bacterial killing. We exploited the susceptibility of Escherichia coli in macrophages to characterize the effects of the respiratory burst on intracellular bacteria. We show that E. coli strains reco...
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Escherichia coli is a common inhabitant of the gastrointestinal tracts of humans and animals. Commensal E. coli, designated as nonpathogenic, are considered to be the majority. This microorganism can be divided into two large groups: pathogenic and commensal E. coli. The pathogenic group is characterized by two more pathotypes: diarrheagenic E. coli (DEC) (with eight subpathotypes) and extraint...
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Avian pathogenic Escherichia coli is an important etiological agent of avian colibacillosis, which manifests as respiratory, hematogenous, meningitic, and enteric infections in poultry. It is also a potential zoonotic threat to human health. The diverse genomes of APEC strains largely hinder disease prevention and control measures. In the current study, pyrosequencing was used to analyze and ch...
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Avian pathogenic Escherichia coli (APEC) strains are associated with respiratory infections, septicemia, cellulitis, peritonitis, and other conditions, since colibacillosis manifests in many ways. The Pho regulon is jointly controlled by the two-component regulatory system PhoBR and by the phosphate-specific transport (Pst) system. To determine the specific roles of the PhoBR regulon and the Ps...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2005
ISSN: 0378-1097
DOI: 10.1016/j.femsle.2005.09.024